THE B CELL DEATH FUNCTION OF OBINUTUZUMAB-HDEL PRODUCED IN PLANT (NICOTIANA BENTHAMIANA L.) IS EQUIVALENT TO OBINUTUZUMAB PRODUCED IN CHO CELLS.

The B cell death function of obinutuzumab-HDEL produced in plant (Nicotiana benthamiana L.) is equivalent to obinutuzumab produced in CHO cells.

Plants have attracted attention as bio-drug production platforms because of their economical and safety benefits.The preliminary efficacy of ZMapp, a cocktail of antibodies produced in N.benthamiana (Nicotiana benthamiana L.), suggested plants may serve as a platform for antibody production.However, ORG PUMPKIN because the amino acid sequences of t

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Waveguide QED with Quadratic Light-Matter Interactions

Quadratic light-matter interactions are nonlinear couplings such that quantum emitters interact with photonic or phononic modes exclusively via the exchange of excitation pairs.Implementable with atomic and solid-state systems, these couplings lead to a plethora of phenomena that have been characterized in the context of cavity QED, where quantum e

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Plant Poly(ADP-Ribose) Polymerase 1 Is a Potential Mediator of Cross-Talk between the Cajal Body Protein Coilin and Salicylic Acid-Mediated Antiviral Defence

The nucleolus and Cajal bodies (CBs) are Socks sub-nuclear domains with well-known roles in RNA metabolism and RNA-protein assembly.However, they also participate in other important aspects of cell functioning.This study uncovers a previously unrecognised mechanism by which these bodies and their components regulate host defences against pathogen a

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A Text-Based Smoking Cessation Intervention for Sexual and Gender Minority Groups: Protocol for a Feasibility Trial

BackgroundSmoking among sexual and gender minority (SGM) groups, which include lesbian, gay, bisexual, transgender, and queer individuals, has been reported to be highly prevalent.This is attributed to several factors, including minority-specific stress and targeted tobacco marketing.Therefore, this population is at an increased risk for tobacco-re

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